High-resolution microscope based on a harmonic source in the water window for imaging at the k-absorption threshold of carbon

PROJECT COST:

337 716 $

PRIMA CONTRIBUTION:

135 000 $

PROJECT DETAILS:

In recent years, significant advances in laser technology have demonstrated that it is possible to generate a tabletop X-ray source covering the spectral window of water. Located between 280 and 540 eV of photon energy, this spectral region is of great interest because it offers the possibility of imaging matter with a spectroscopic contrast specific to carbon- and nitrogen-rich chemical entities, via their k-absorption thresholds. In this region of the X-ray spectrum, water absorbs very little, enabling high-resolution spectroscopy and microscopy in aqueous solution. As part of this project, we propose to go beyond recent achievements by developing a prototype microscope based on a full-field mode, which will enable high-resolution imaging at the carbon K-edge. The goal is to achieve a spatial resolution of less than 100 nanometers. To do so, we will build on two major developments that have been achieved in recent years at the INRS-ÉMT’s Advanced Laser Light Source laboratory.
On the one hand, we have developed a system capable of generating and characterizing photons beyond the K-edge of carbon. This X-ray source is unique in Canada. Furthermore, we have recently installed an infrared laser source delivering 2.8 TW of peak power in pulses lasting two optical cycles. This laser, the only one of its kind in the world, will significantly increase the photon flux in the spectral region corresponding to water, which is essential for the development of the microscope.