Development of coating by plasma process for medical devices with adjustable antibacterial properties
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Central venous catheters, used for nutrient and drug administration, carry a significant risk of microbial contamination in patients requiring long-term treatment, such as those in intensive care or undergoing cancer therapy.
The objective of Professor Diego Mantovani’s project at Laval University is to develop an anti-adhesive and antibacterial coating that: i) utilizes metallic agents with proven antibacterial efficacy, ii) enables controlled long-term release, iii) is applied via a plasma process, and iv) coats both the internal and external surfaces of catheters.
This approach aims to prevent infections by inhibiting the formation of bacterial biofilms, the protective structures that shield bacteria from the immune system and antibiotics. The project will provide a unique multidisciplinary training environment for 3 doctoral students, 2 master’s students, 2 postdoctoral researchers, and several undergraduate summer interns.
Quebec-based Plasmionique Inc. will benefit from expanding its expertise in plasma-based coating systems and surface treatments for the biomedical, pharmaceutical, biotechnological, and medical device sectors.
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